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Fibroblasts are specialized cells deemed essential in producing new collagen fibers, vital components for structural support in various tissues
114,115,116 Whereas the canonical reactions catalysed by CBS and CSE within the trans-sulphuration pathway sequentially convert homocysteine into cysteine, both enzymes catalyse a number of alternative H 2 S-yielding reactions, using as substrates different combinations of these very same sulphur amino acids (reviewed e.g
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Nature 417 , 299304 (2002)
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